MO · O'Fallon · Updated October 15, 2026

Medical Assistant jobs in O'Fallon, MO

Medical Assistants in the O'Fallon area earn a median of $20.50 per hour, about $42,630 a year, and the middle half of them earn between $18.38 and $21.75. That ranks 150th of 380 U.S. metro areas for medical assistant pay, and 118th of 339 once local prices are factored in. 6 open roles with published pay are listed for O'Fallon and its metro area. Tell us your role and we email current openings near O'Fallon.

Open Medical Assistant roles near O'Fallon

Roles in other cities of the St. Louis area.

More open Medical Assistant roles in O'Fallon

1 more open role from employers in O'Fallon. Each employer’s range arrives with your free pay report.

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Named employers near O'Fallon, what they pay and the roles open now. Free for candidates, email only.

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Who is hiring medical assistants near O'Fallon

EmployerRolesMedian pay / hour
Hospital Sisters Health System5$23.27
OSF Healthcare System1$22.21

Medical Assistant pay in O'Fallon, MO

The metro median is 8% above the Missouri statewide median of $18.90 per hour. Nationally the median is $21.25 per hour. BLS counts about 5,040 medical assistants employed in the St. Louis metro area, 3.8 per 1,000 jobs. Employment is less concentrated here than in the country as a whole (location quotient 0.73).

LevelPer hourPer yearCompared with U.S.
Lowest 10%$17.53$36,46018% below U.S. median
Lower quartile$18.38$38,23014% below U.S. median
Median$20.50$42,6304% below U.S. median
Upper quartile$21.75$45,2402% above U.S. median
Top 10%$22.81$47,4407% above U.S. median

How O'Fallon ranks

  • 150th of 380 U.S. metro areas by median hourly pay
  • 118th of 339 after adjusting for local prices
  • 2nd of 8 Missouri metro areas

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2024, Medical Assistants (SOC 31-9092), all industries. This is what employers report paying, not an offer for a specific role.

What your pay buys in O'Fallon

  • Overall prices in St. Louis run 5% below the U.S. average (index 95.1, U.S. = 100).
  • Housing is the biggest driver: 21% below the U.S. average (index 79.0).
  • Adjusted for local prices, a $20.50 median hour buys what $21.56 buys at the national price level, 1% above the national median.

Source: U.S. Bureau of Economic Analysis, Regional Price Parities by metropolitan area, 2024. Prices are for the metro area, not for a single neighborhood.

Estimate your O'Fallon paycheck

Estimated weekly gross$738
  • Per year: $36,900
  • Per month: $3,075

Gross pay before taxes and benefits, from BLS pay levels for the St. Louis metro area. For take-home pay use the take-home pay calculator.

Travel assignment per diem in O'Fallon

ItemFederal rate
Lodging per night$150
Meals and incidentals per day$86
Per week (7 nights, 7 days)$1,652
13-week assignment$21,476

Travel medical assistant assignments commonly pay housing and meals stipends. The GSA per diem is the federal benchmark for what those stipends can be tax-free. Whether a stipend is tax-free for you depends on keeping a valid tax home, so confirm with your recruiter and a tax professional. Compare with your offer in the travel pay calculator.

Source: U.S. General Services Administration per diem rates, fiscal year 2026 (average across months).

Hospitals in O'Fallon

CMS lists 1 hospital in O'Fallon, 1 of the 1 rated ones with 4 or 5 stars. Hospitals are a major employer of medical assistants.

HospitalTypeOwnershipCMS ratingEmergency
Progress West Hospital
Ofallon, MO
Acute careNonprofit4 of 5Yes

Source: CMS Hospital General Information, public data. A directory of hospitals, not a list of our clients.

Primary care shortage areas in St. Charles County

HRSA lists 1 active primary care shortage designation that include St. Charles County (1 population-group). The highest-scoring one rates 17 on a 0 to 25 scale, where a higher score means a greater shortage.

Shortage areas are where demand for nurses, nurse practitioners, physician assistants and other clinicians is greatest. Federal loan repayment programs such as the NHSC and Nurse Corps cover some clinicians who work at eligible shortage-area sites. Eligibility is set by each program and by the site, so ask your recruiter before you plan around it.

Source: HRSA Health Professional Shortage Areas data warehouse, designated areas only. A designation can cover part of a county.

Medical Assistant pay in nearby cities

CityDistanceMedian payPopulation
St. Peters, MO6 mi$20.50/hr61,398
St. Charles, MO11 mi$20.50/hr72,458
Columbia, MO87 mi$18.07/hr130,900
Springfield, IL90 mi$19.52/hr112,949
Decatur, IL121 mi$19.51/hr68,763
Peoria, IL148 mi$20.75/hr111,696

Medical Assistant jobs in Missouri · Medical Assistant jobs nationwide

License and tax basics in Missouri

Medical assistant program or equivalent experience. Credentials are issued state by state, so confirm what Missouri requires for your role with the Missouri licensing board and with your recruiter before you commit to a start date.

Missouri taxes wage income. Use your own rates in the take-home pay calculator.

Missouri state guide

Other healthcare roles in O'Fallon

O'Fallon city guide: hospitals, employers and licensing

Common questions

How much do medical assistants make in O'Fallon, MO?

Medical Assistants in the St. Louis metro area have a median pay of $20.50 per hour, about $42,630 a year. The middle half earn between $18.38 and $21.75 per hour (BLS, May 2024).

Is O'Fallon a good place for medical assistants once cost of living is counted?

St. Louis ranks 118th of 339 metro areas for medical assistant pay after adjusting for local prices, and 150th of 380 before adjusting. Overall prices run 5% below the U.S. average.

Who is hiring medical assistants in O'Fallon?

We list 6 open roles with published pay from 2 employers in the St. Louis area. Your free report adds named employers and pay near O'Fallon.

Do I need a Missouri license to work in O'Fallon as a medical assistant?

Medical assistant program or equivalent experience. Credentials are issued state by state, so confirm what Missouri requires for your role with the Missouri licensing board and with your recruiter before you commit to a start date. Confirm with the board before you accept a role.

Is O'Fallon in a shortage area?

HRSA lists 1 active primary care shortage designation that include St. Charles County. Shortage areas often have more openings, and some loan repayment programs cover clinicians who work at eligible sites.

What is the per diem for a travel assignment in O'Fallon?

The federal per diem benchmark in O'Fallon is $150 a night for lodging and $86 a day for meals and incidentals, about $1,652 a week (GSA, fiscal year 2026). Your actual stipend depends on the assignment and your tax home.

Does Valorem Health place medical assistants in O'Fallon?

Yes. We place healthcare staff in O'Fallon and across Missouri. Tell us your profession and we email the roles open near O'Fallon.

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What do employers near O'Fallon pay medical assistants? Get the report.

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    Pay for your role at other hospitals

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    What they are offering now

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The Joint Commission Gold Seal of Approval: Health Care Staffing Services Certification, since 2022American Staffing Association memberNATHO member: National Association of Travel Healthcare OrganizationsNALTO member: National Association of Locum Tenens Organizations

Pay report · Medical Assistant near O'Fallon, MO
Valorem Health Shift ReportFrom your recruiting team · [email protected]

Your Medical Assistant pay reportTop-paying hospitals shown · your Missouri list by name comes with the full report

1Pay for your role at other hospitals

  • University of Missouri Health CareColumbia, MO · 3 postings$21.49/ hr$17–$28
  • Seattle Children'sSeattle, WA · 11 postings$33.96/ hr$27–$41
  • CommonSpirit HealthSeattle, WA · 21 postings$31.77/ hr$26–$42
  • Sharp HealthCareSan Diego, CA · 11 postings$31.60/ hr$26–$37

Median posted pay per hour, with the range each employer published. Request your Missouri list

2What they are offering now

Low$17Median$21.49High$28

3 Medical Assistant postings with published pay in Missouri, 3 of them posted in the last 30 days. Month-by-month history by employer comes with your full report.

3Open now: 3 Medical Assistant roles

  1. Medical Assistant - Outpatient Clinics - Multiple Locations!Permanent
    $16.68–$26.31/ hour
    University of Missouri Health Care · Columbia, MO · posted today
  2. Medical Assistant - Jefferson City Clinics (Click For Locations)Permanent
    $16.68–$26.31/ hour
    University of Missouri Health Care · Jefferson City, MO · posted 7 days ago

+ 1 more in your report. Each one has pay, shift and start date.

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