SD · Sioux Falls · Updated October 15, 2026

Medical Assistant jobs in Sioux Falls, SD

Medical Assistants in the Sioux Falls area earn a median of $19.50 per hour, about $40,560 a year, and the middle half of them earn between $17.66 and $21.47. That ranks 182nd of 380 U.S. metro areas for medical assistant pay, and 120th of 339 once local prices are factored in. 11 open roles with published pay are listed for Sioux Falls. Tell us your role and we email current openings near Sioux Falls.

Open Medical Assistant roles in Sioux Falls

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Medical Assistant pay in Sioux Falls, SD

The metro median is 3% above the South Dakota statewide median of $18.92 per hour. Nationally the median is $21.25 per hour. BLS counts about 540 medical assistants employed in the Sioux Falls metro area, 3.1 per 1,000 jobs. Employment is less concentrated here than in the country as a whole (location quotient 0.60).

LevelPer hourPer yearCompared with U.S.
Lowest 10%$15.12$31,45029% below U.S. median
Lower quartile$17.66$36,73017% below U.S. median
Median$19.50$40,5608% below U.S. median
Upper quartile$21.47$44,6601% above U.S. median
Top 10%$23.79$49,48012% above U.S. median

How Sioux Falls ranks

  • 182nd of 380 U.S. metro areas by median hourly pay
  • 120th of 339 after adjusting for local prices

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2024, Medical Assistants (SOC 31-9092), all industries. This is what employers report paying, not an offer for a specific role.

What your pay buys in Sioux Falls

  • Overall prices in Sioux Falls run 9% below the U.S. average (index 90.6, U.S. = 100).
  • Housing is the biggest driver: 22% below the U.S. average (index 77.6).
  • Adjusted for local prices, a $19.50 median hour buys what $21.52 buys at the national price level, 1% above the national median.

Source: U.S. Bureau of Economic Analysis, Regional Price Parities by metropolitan area, 2024. Prices are for the metro area, not for a single neighborhood.

Estimate your Sioux Falls paycheck

Estimated weekly gross$702
  • Per year: $35,100
  • Per month: $2,925
  • South Dakota has no state income tax on wages.

Gross pay before taxes and benefits, from BLS pay levels for the Sioux Falls metro area. For take-home pay use the take-home pay calculator.

Travel assignment per diem in Sioux Falls

ItemFederal rate
Lodging per night$110
Meals and incidentals per day$68
Per week (7 nights, 7 days)$1,246
13-week assignment$16,198

Travel medical assistant assignments commonly pay housing and meals stipends. The GSA per diem is the federal benchmark for what those stipends can be tax-free (this is the standard rate that applies here). Whether a stipend is tax-free for you depends on keeping a valid tax home, so confirm with your recruiter and a tax professional. Compare with your offer in the travel pay calculator.

Source: U.S. General Services Administration per diem rates, fiscal year 2026 (average across months).

Hospitals in Sioux Falls

CMS lists 6 hospitals in Sioux Falls, 4 of the 4 rated ones with 4 or 5 stars. Hospitals are a major employer of medical assistants.

HospitalTypeOwnershipCMS ratingEmergency
Avera Heart Hospital Of South Dakota
Sioux Falls, SD
Acute careFor-profit5 of 5Yes
Sanford Usd Medical Center
Sioux Falls, SD
Acute careNonprofit5 of 5Yes
Sioux Falls Va Medical Center
Sioux Falls, SD
Acute Care - Veterans AdministrationGovernment and federal5 of 5Yes
Avera Mckennan Hospital & University Health Center
Sioux Falls, SD
Acute careNonprofit4 of 5Yes
Lifescape
Sioux Falls, SD
Children'sNonprofitNot ratedNo
Sioux Falls Specialty Hospital
Sioux Falls, SD
Acute careFor-profitNot ratedNo

Source: CMS Hospital General Information, public data. A directory of hospitals, not a list of our clients.

Primary care shortage areas in Minnehaha County

HRSA lists 3 active primary care shortage designations that include Minnehaha County (3 facility). The highest-scoring one rates 18 on a 0 to 25 scale, where a higher score means a greater shortage.

Shortage areas are where demand for nurses, nurse practitioners, physician assistants and other clinicians is greatest. Federal loan repayment programs such as the NHSC and Nurse Corps cover some clinicians who work at eligible shortage-area sites. Eligibility is set by each program and by the site, so ask your recruiter before you plan around it.

Source: HRSA Health Professional Shortage Areas data warehouse, designated areas only. A designation can cover part of a county.

Medical Assistant pay in nearby cities

CityDistanceMedian payPopulation
Sioux City, IA74 mi$19.67/hr86,875
Omaha, NE161 mi$22.76/hr489,265
Council Bluffs, IA165 mi$22.76/hr62,665
Bellevue, NE170 mi$22.76/hr64,777
Eden Prairie, MN186 mi$24.12/hr62,905
St. Cloud, MN186 mi$22.47/hr72,145

Medical Assistant jobs in South Dakota · Medical Assistant jobs nationwide

License and tax basics in South Dakota

Medical assistant program or equivalent experience. Credentials are issued state by state, so confirm what South Dakota requires for your role with the South Dakota licensing board and with your recruiter before you commit to a start date.

South Dakota does not tax wage income at the state level, so take-home pay is higher than the same gross pay in a state that does.

South Dakota state guide

Other healthcare roles in Sioux Falls

Sioux Falls city guide: hospitals, employers and licensing

Common questions

How much do medical assistants make in Sioux Falls, SD?

Medical Assistants in the Sioux Falls metro area have a median pay of $19.50 per hour, about $40,560 a year. The middle half earn between $17.66 and $21.47 per hour (BLS, May 2024).

Is Sioux Falls a good place for medical assistants once cost of living is counted?

Sioux Falls ranks 120th of 339 metro areas for medical assistant pay after adjusting for local prices, and 182nd of 380 before adjusting. Overall prices run 9% below the U.S. average.

Who is hiring medical assistants in Sioux Falls?

We list 11 open roles with published pay from 1 employer in Sioux Falls. Your free report adds named employers and pay near Sioux Falls.

Do I need a South Dakota license to work in Sioux Falls as a medical assistant?

Medical assistant program or equivalent experience. Credentials are issued state by state, so confirm what South Dakota requires for your role with the South Dakota licensing board and with your recruiter before you commit to a start date. Confirm with the board before you accept a role.

Is Sioux Falls in a shortage area?

HRSA lists 3 active primary care shortage designations that include Minnehaha County. Shortage areas often have more openings, and some loan repayment programs cover clinicians who work at eligible sites.

What is the per diem for a travel assignment in Sioux Falls?

The federal per diem benchmark in Sioux Falls is $110 a night for lodging and $68 a day for meals and incidentals, about $1,246 a week (GSA, fiscal year 2026). Your actual stipend depends on the assignment and your tax home.

Does Valorem Health place medical assistants in Sioux Falls?

Yes. We place healthcare staff in Sioux Falls and across South Dakota. Tell us your profession and we email the roles open near Sioux Falls.

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Pay report · Medical Assistant near Sioux Falls, SD
Valorem Health Shift ReportFrom your recruiting team · [email protected]

Your Medical Assistant pay reportTop-paying hospitals shown · your South Dakota list by name comes with the full report

1Pay for your role at other hospitals

  • Avera HealthSioux Falls, SD · 21 postings$30.62/ hr$18–$41
  • Monument HealthRapid City, SD · 13 postings$24.59/ hr$20–$29
  • Seattle Children'sSeattle, WA · 11 postings$33.96/ hr$27–$41
  • CommonSpirit HealthSeattle, WA · 21 postings$31.77/ hr$26–$42

Median posted pay per hour, with the range each employer published. Request your South Dakota list

2What they are offering now

Low$20Median$24.59High$41

34 Medical Assistant postings with published pay in South Dakota, 27 of them posted in the last 30 days. Month-by-month history by employer comes with your full report.

3Open now: 34 Medical Assistant roles

  1. Registered Nurse (RN) or Licensed Practical Nurse (LPN) or Medical Assistant | Comprehensive Breast ClinicPermanent
    $20.00–$41.25/ hour
    Avera Health · Sioux Falls, SD · posted today
  2. Registered Nurse (RN) or Licensed Practical Nurse (LPN) or Medical Assistant | Wound Care ClinicPermanent
    $20.00–$41.25/ hour
    Avera Health · Sioux Falls, SD · posted yesterday

+ 32 more in your report. Each one has pay, shift and start date.

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