SC · Greenville · Updated October 15, 2026

Nurse Practitioner jobs in Greenville, SC

The median nurse practitioner pay in the Greenville area is $53.15 per hour ($110,550 a year), with the typical range running from $48.68 to $59.58. That ranks 336th of 372 U.S. metro areas for nurse practitioner pay, and 317th of 336 once local prices are factored in. The CMS hospital directory lists 4 hospitals in Greenville. The free report below lists employers near Greenville and what they pay.

More open Nurse Practitioner roles in Greenville

1 more open role from employers in Greenville. Each employer’s range arrives with your free pay report.

Nurse Practitioner pay in Greenville, SC

The metro median is 5% below the South Carolina statewide median of $55.88 per hour. Nationally the median is $62.12 per hour. BLS counts about 1,130 nurse practitioners employed in the Greenville-Anderson-Greer metro area, 2.6 per 1,000 jobs. Employment is more concentrated here than in the country as a whole (location quotient 1.32).

LevelPer hourPer yearCompared with U.S.
Lowest 10%$23.62$49,13062% below U.S. median
Lower quartile$48.68$101,25022% below U.S. median
Median$53.15$110,55014% below U.S. median
Upper quartile$59.58$123,9304% below U.S. median
Top 10%$65.40$136,0305% above U.S. median

How Greenville ranks

  • 336th of 372 U.S. metro areas by median hourly pay
  • 317th of 336 after adjusting for local prices
  • 7th of 8 South Carolina metro areas

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2024, Nurse Practitioners (SOC 29-1171), all industries. This is what employers report paying, not an offer for a specific role.

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What your pay buys in Greenville

  • Overall prices in Greenville-Anderson-Greer run 7% below the U.S. average (index 93.3, U.S. = 100).
  • Housing is the biggest driver: 23% below the U.S. average (index 76.8).
  • Adjusted for local prices, a $53.15 median hour buys what $56.99 buys at the national price level, 8% below the national median.

Source: U.S. Bureau of Economic Analysis, Regional Price Parities by metropolitan area, 2024. Prices are for the metro area, not for a single neighborhood.

Estimate your Greenville paycheck

Estimated weekly gross$1,913
  • Per year: $95,670
  • Per month: $7,972

Gross pay before taxes and benefits, from BLS pay levels for the Greenville-Anderson-Greer metro area. For take-home pay use the take-home pay calculator.

Travel assignment per diem in Greenville

ItemFederal rate
Lodging per night$110
Meals and incidentals per day$68
Per week (7 nights, 7 days)$1,246
13-week assignment$16,198

Travel nurse practitioner assignments commonly pay housing and meals stipends. The GSA per diem is the federal benchmark for what those stipends can be tax-free (this is the standard rate that applies here). Whether a stipend is tax-free for you depends on keeping a valid tax home, so confirm with your recruiter and a tax professional. Compare with your offer in the travel pay calculator.

Source: U.S. General Services Administration per diem rates, fiscal year 2026 (average across months).

Open Nurse Practitioner roles in South Carolina

Nearest open roles with published pay. Your free report adds roles in Greenville as they open.

All Nurse Practitioner jobs in South Carolina

Hospitals in Greenville

CMS lists 4 hospitals in Greenville, 3 of the 3 rated ones with 4 or 5 stars. Hospitals are a major employer of nurse practitioners.

HospitalTypeOwnershipCMS ratingEmergency
Prisma Health Patewood Hospital
Greenville, SC
Acute careNonprofit5 of 5No
Prisma Health Greenville Memorial Hospital
Greenville, SC
Acute careNonprofit4 of 5No
St Francis-Downtown
Greenville, SC
Acute careNonprofit4 of 5Yes
Shriners Hospitals For Children
Greenville, SC
Children'sNonprofitNot ratedNo

Source: CMS Hospital General Information, public data. A directory of hospitals, not a list of our clients.

Primary care shortage areas in Greenville County

HRSA lists 4 active primary care shortage designations that include Greenville County (1 population-group, 3 facility). The highest-scoring one rates 12 on a 0 to 25 scale, where a higher score means a greater shortage.

Shortage areas are where demand for nurses, nurse practitioners, physician assistants and other clinicians is greatest. Federal loan repayment programs such as the NHSC and Nurse Corps cover some clinicians who work at eligible shortage-area sites. Eligibility is set by each program and by the site, so ask your recruiter before you plan around it.

Source: HRSA Health Professional Shortage Areas data warehouse, designated areas only. A designation can cover part of a county.

Nurse Practitioner pay in nearby cities

CityDistanceMedian payPopulation
Asheville, NC52 mi$57.55/hr94,992
Gastonia, NC72 mi$62.81/hr85,535
Rock Hill, SC76 mi$62.81/hr75,798
Athens, GA84 mi$59.25/hr128,691
Charlotte, NC90 mi$62.81/hr943,476
Huntersville, NC93 mi$62.81/hr67,087

Nurse Practitioner jobs in South Carolina · Nurse Practitioner jobs nationwide

License and tax basics in South Carolina

South Carolina is in the Nurse Licensure Compact, so an RN or LPN/LVN with a multistate license from another compact state can work here without a new license. Nurses whose home state is not in the compact apply for a South Carolina license by endorsement.

South Carolina taxes wage income. Use your own rates in the take-home pay calculator.

South Carolina state guide · Nurse Licensure Compact guide

Other healthcare roles in Greenville

Greenville city guide: hospitals, employers and licensing

Common questions

How much do nurse practitioners make in Greenville, SC?

Nurse Practitioners in the Greenville-Anderson-Greer metro area have a median pay of $53.15 per hour, about $110,550 a year. The middle half earn between $48.68 and $59.58 per hour (BLS, May 2024).

Is Greenville a good place for nurse practitioners once cost of living is counted?

Greenville-Anderson-Greer ranks 317th of 336 metro areas for nurse practitioner pay after adjusting for local prices, and 336th of 372 before adjusting. Overall prices run 7% below the U.S. average.

Where do nurse practitioners work in Greenville?

CMS lists 4 hospitals in Greenville, led by Prisma Health Patewood Hospital. Ask for the free report to see current openings and pay.

Do I need a South Carolina license to work in Greenville as a nurse practitioner?

South Carolina is in the Nurse Licensure Compact, so an RN or LPN/LVN with a multistate license from another compact state can work here without a new license. Nurses whose home state is not in the compact apply for a South Carolina license by endorsement. Confirm with the board before you accept a role.

Is Greenville in a shortage area?

HRSA lists 4 active primary care shortage designations that include Greenville County. Shortage areas often have more openings, and some loan repayment programs cover clinicians who work at eligible sites.

What is the per diem for a travel assignment in Greenville?

The federal per diem benchmark in Greenville is $110 a night for lodging and $68 a day for meals and incidentals, about $1,246 a week (GSA, fiscal year 2026). Your actual stipend depends on the assignment and your tax home.

Does Valorem Health place nurse practitioners in Greenville?

Yes. We place healthcare staff in Greenville and across South Carolina. Tell us your profession and we email the roles open near Greenville.

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What do employers near Greenville pay nurse practitioners? Get the report.

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    Pay for your role at other hospitals

    The hourly pay at named employers near you, so you see who pays most.

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    What they are offering now

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Pay report · NP near Greenville, SC
Valorem Health Shift ReportFrom your recruiting team · [email protected]

Your NP pay reportTop-paying employers shown · your South Carolina list by name comes with the full report

1Pay for your role at other employers

  • Apogee Medical Group, South Carolina, PCColumbia, SC · 1 wage offer$86.12/ hr$86–$86
  • MarinHealthGreenbrae, CA · 4 postings$96.91/ hr$86–$108
  • Sharp HealthCareSan Diego, CA · 6 postings$92.12/ hr$80–$104
  • Sharp HealthcareSan Diego, CA · 3 postings$92.12/ hr$80–$104

Median pay per hour, with the range each employer published or reported in federal filings. Request your South Carolina list

2What they are offering now

Low$52Median$67.39High$89

424 NP postings with published pay in the US, 363 of them posted in the last 30 days. Month-by-month history by employer comes with your full report.

3Open now: 1 NP roles

  1. Nurse Practitioner (Cardiology)Permanent
    $109k–$187k/ year
    Veterans Health Administration · Myrtle Beach, SC · posted 2 days ago

Each one has pay, shift and start date.

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