MO · St. Charles · Updated October 15, 2026

Registered Nurse jobs in St. Charles, MO

The median registered nurse pay in the St. Charles area is $39.69 per hour ($82,560 a year), with the typical range running from $33.06 to $46.53. 2 open roles with published pay are listed for St. Charles. The CMS hospital directory lists 2 hospitals in St. Charles. The free report below lists employers near St. Charles and what they pay.

Open Registered Nurse roles in St. Charles

More open Registered Nurse roles in St. Charles

9 more open roles from employers in St. Charles. Each employer’s range arrives with your free pay report.

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Named employers near St. Charles, what they pay and the roles open now. Free for candidates, email only.

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Who is hiring registered nurses near St. Charles

EmployerRolesMedian pay / hour
Select Medical1$47.06
Acadia Healthcare1$47.50

Registered Nurse pay in St. Charles, MO

The metro median is 3% above the Missouri statewide median of $38.35 per hour. Nationally the median is $45.00 per hour. BLS counts about 33,660 registered nurses employed in the St. Louis metro area, 25.1 per 1,000 jobs. Employment is more concentrated here than in the country as a whole (location quotient 1.18).

LevelPer hourPer yearCompared with U.S.
Lowest 10%$29.80$61,98034% below U.S. median
Lower quartile$33.06$68,76027% below U.S. median
Median$39.69$82,56012% below U.S. median
Upper quartile$46.53$96,7803% above U.S. median
Top 10%$50.79$105,64013% above U.S. median

How St. Charles ranks

  • 181st of 379 U.S. metro areas by median hourly pay
  • 220th of 335 after adjusting for local prices
  • 2nd of 8 Missouri metro areas

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2024, Registered Nurses (SOC 29-1141), all industries. This is what employers report paying, not an offer for a specific role.

What your pay buys in St. Charles

  • Overall prices in St. Louis run 5% below the U.S. average (index 95.1, U.S. = 100).
  • Housing is the biggest driver: 21% below the U.S. average (index 79.0).
  • Adjusted for local prices, a $39.69 median hour buys what $41.74 buys at the national price level, 7% below the national median.

Source: U.S. Bureau of Economic Analysis, Regional Price Parities by metropolitan area, 2024. Prices are for the metro area, not for a single neighborhood.

Estimate your St. Charles paycheck

Estimated weekly gross$1,429
  • Per year: $71,442
  • Per month: $5,954

Gross pay before taxes and benefits, from BLS pay levels for the St. Louis metro area. For take-home pay use the take-home pay calculator.

Travel assignment per diem in St. Charles

ItemFederal rate
Lodging per night$150
Meals and incidentals per day$86
Per week (7 nights, 7 days)$1,652
13-week assignment$21,476

Travel registered nurse assignments commonly pay housing and meals stipends. The GSA per diem is the federal benchmark for what those stipends can be tax-free. Whether a stipend is tax-free for you depends on keeping a valid tax home, so confirm with your recruiter and a tax professional. Compare with your offer in the travel pay calculator.

Source: U.S. General Services Administration per diem rates, fiscal year 2026 (average across months).

Hospitals in St. Charles

CMS lists 2 hospitals in St. Charles, 0 of the 1 rated ones with 4 or 5 stars. Hospitals are a major employer of registered nurses.

HospitalTypeOwnershipCMS ratingEmergency
Ssm St Joseph Health Center
Saint Charles, MO
Acute careNonprofit3 of 5Yes
Centerpointe Hospital
Saint Charles, MO
PsychiatricFor-profitNot ratedNo

Source: CMS Hospital General Information, public data. A directory of hospitals, not a list of our clients.

Primary care shortage areas in St. Charles County

HRSA lists 1 active primary care shortage designation that include St. Charles County (1 population-group). The highest-scoring one rates 17 on a 0 to 25 scale, where a higher score means a greater shortage.

Shortage areas are where demand for nurses, nurse practitioners, physician assistants and other clinicians is greatest. Federal loan repayment programs such as the NHSC and Nurse Corps cover some clinicians who work at eligible shortage-area sites. Eligibility is set by each program and by the site, so ask your recruiter before you plan around it.

Source: HRSA Health Professional Shortage Areas data warehouse, designated areas only. A designation can cover part of a county.

Registered Nurse pay in nearby cities

CityDistanceMedian payPopulation
St. Peters, MO5 mi$39.69/hr61,398
Florissant, MO10 mi$39.69/hr51,290
Springfield, IL83 mi$39.27/hr112,949
Columbia, MO98 mi$39.12/hr130,900
Decatur, IL112 mi$40.44/hr68,763
Bloomington, IL142 mi$38.49/hr79,232

Registered Nurse jobs in Missouri · Registered Nurse jobs nationwide

License and tax basics in Missouri

Missouri is in the Nurse Licensure Compact, so an RN or LPN/LVN with a multistate license from another compact state can work here without a new license. Nurses whose home state is not in the compact apply for a Missouri license by endorsement.

Missouri taxes wage income. Use your own rates in the take-home pay calculator.

Missouri state guide · Nurse Licensure Compact guide

Other healthcare roles in St. Charles

St. Charles city guide: hospitals, employers and licensing

Common questions

How much do registered nurses make in St. Charles, MO?

Registered Nurses in the St. Louis metro area have a median pay of $39.69 per hour, about $82,560 a year. The middle half earn between $33.06 and $46.53 per hour (BLS, May 2024).

Is St. Charles a good place for registered nurses once cost of living is counted?

St. Louis ranks 220th of 335 metro areas for registered nurse pay after adjusting for local prices, and 181st of 379 before adjusting. Overall prices run 5% below the U.S. average.

Who is hiring registered nurses in St. Charles?

We list 2 open roles with published pay from 2 employers in St. Charles. Your free report adds named employers and pay near St. Charles.

Do I need a Missouri license to work in St. Charles as a registered nurse?

Missouri is in the Nurse Licensure Compact, so an RN or LPN/LVN with a multistate license from another compact state can work here without a new license. Nurses whose home state is not in the compact apply for a Missouri license by endorsement. Confirm with the board before you accept a role.

Is St. Charles in a shortage area?

HRSA lists 1 active primary care shortage designation that include St. Charles County. Shortage areas often have more openings, and some loan repayment programs cover clinicians who work at eligible sites.

What is the per diem for a travel assignment in St. Charles?

The federal per diem benchmark in St. Charles is $150 a night for lodging and $86 a day for meals and incidentals, about $1,652 a week (GSA, fiscal year 2026). Your actual stipend depends on the assignment and your tax home.

Does Valorem Health place registered nurses in St. Charles?

Yes. We place healthcare staff in St. Charles and across Missouri. Tell us your profession and we email the roles open near St. Charles.

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What do employers near St. Charles pay registered nurses? Get the report.

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    Pay for your role at other hospitals

    The hourly pay at named employers near you, so you see who pays most.

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    What they are offering now

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The Joint Commission Gold Seal of Approval: Health Care Staffing Services Certification, since 2022American Staffing Association memberNATHO member: National Association of Travel Healthcare OrganizationsNALTO member: National Association of Locum Tenens Organizations

Pay report · RN near St. Charles, MO
Valorem Health Shift ReportFrom your recruiting team · [email protected]

Your RN pay reportSt. Charles, MO · pay published by employers and employer-reported wage offers in federal filings

1Pay for your role at other employers

  • Veterans Health AdministrationKansas City, MO · 8 postings$52.14/ hr$33–$76
  • Select MedicalSaint Louis, MO · 9 postings$46.00/ hr$34–$56
  • University of Missouri Health CareColumbia, MO · 2 postings$39.56/ hr$30–$51
  • Truman Medical Centers, Inc.Kansas City, MO · 2 wage offers$32.45/ hr$32–$33

Median pay per hour, with the range each employer published or reported in federal filings.

2What they are offering now

Low$34Median$46.61High$62

22 RN postings with published pay in Missouri, 21 of them posted in the last 30 days. Month-by-month history by employer comes with your full report.

3Open now: 22 RN roles

  1. Registered Nurse - Outpatient Mental HealthPer diem
    $75k–$154k/ year
    Veterans Health Administration · Saint Louis, MO · posted today
  2. Registered Nurse - Mental HealthPermanent
    $75k–$154k/ year
    Veterans Health Administration · Saint Louis, MO · posted today

+ 20 more in your report. Each one has pay, shift and start date.

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