SC · Florence · Updated October 15, 2026

Registered Nurse jobs in Florence, SC

Pay for registered nurses in the Florence area centers on $38.57 per hour, or about $80,220 a year. The lower quarter earns under $31.14 and the upper quarter over $53.39. The CMS hospital directory lists 2 hospitals in Florence. That ranks 245th of 379 U.S. metro areas for registered nurse pay, and 116th of 335 once local prices are factored in. Tell us your role and we email current openings near Florence.

Open Registered Nurse roles in Florence

More open Registered Nurse roles in Florence

2 more open roles from employers in Florence. Each employer’s range arrives with your free pay report.

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Named employers near Florence, what they pay and the roles open now. Free for candidates, email only.

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Who is hiring registered nurses near Florence

EmployerRolesMedian pay / hour
Select Medical2$46.59
Amedisys1$34.38

Registered Nurse pay in Florence, SC

The metro median is in line with the South Carolina statewide median of $38.41 per hour. Nationally the median is $45.00 per hour. BLS counts about 3,060 registered nurses employed in the Florence metro area, 34.0 per 1,000 jobs. Employment is more concentrated here than in the country as a whole (location quotient 1.60).

LevelPer hourPer yearCompared with U.S.
Lowest 10%$30.75$63,96032% below U.S. median
Lower quartile$31.14$64,77031% below U.S. median
Median$38.57$80,22014% below U.S. median
Upper quartile$53.39$111,05019% above U.S. median
Top 10%$79.62$165,61077% above U.S. median

How Florence ranks

  • 245th of 379 U.S. metro areas by median hourly pay
  • 116th of 335 after adjusting for local prices
  • 4th of 8 South Carolina metro areas

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2024, Registered Nurses (SOC 29-1141), all industries. This is what employers report paying, not an offer for a specific role.

What your pay buys in Florence

  • Overall prices in Florence run 13% below the U.S. average (index 86.8, U.S. = 100).
  • Housing is the biggest driver: 48% below the U.S. average (index 52.4).
  • Adjusted for local prices, a $38.57 median hour buys what $44.45 buys at the national price level, 1% below the national median.

Source: U.S. Bureau of Economic Analysis, Regional Price Parities by metropolitan area, 2024. Prices are for the metro area, not for a single neighborhood.

Estimate your Florence paycheck

Estimated weekly gross$1,389
  • Per year: $69,426
  • Per month: $5,786

Gross pay before taxes and benefits, from BLS pay levels for the Florence metro area. For take-home pay use the take-home pay calculator.

Travel assignment per diem in Florence

ItemFederal rate
Lodging per night$110
Meals and incidentals per day$68
Per week (7 nights, 7 days)$1,246
13-week assignment$16,198

Travel registered nurse assignments commonly pay housing and meals stipends. The GSA per diem is the federal benchmark for what those stipends can be tax-free (this is the standard rate that applies here). Whether a stipend is tax-free for you depends on keeping a valid tax home, so confirm with your recruiter and a tax professional. Compare with your offer in the travel pay calculator.

Source: U.S. General Services Administration per diem rates, fiscal year 2026 (average across months).

Hospitals in Florence

CMS lists 2 hospitals in Florence, 0 of the 2 rated ones with 4 or 5 stars. Hospitals are a major employer of registered nurses.

HospitalTypeOwnershipCMS ratingEmergency
Mcleod Regional Medical Center-Pee Dee
Florence, SC
Acute careNonprofit3 of 5Yes
Musc Health Florence Medical Center
Florence, SC
Acute careGovernment and federal3 of 5Yes

Source: CMS Hospital General Information, public data. A directory of hospitals, not a list of our clients.

Primary care shortage areas in Florence County

HRSA lists 3 active primary care shortage designations that include Florence County (1 population-group, 2 facility). The highest-scoring one rates 18 on a 0 to 25 scale, where a higher score means a greater shortage.

Shortage areas are where demand for nurses, nurse practitioners, physician assistants and other clinicians is greatest. Federal loan repayment programs such as the NHSC and Nurse Corps cover some clinicians who work at eligible shortage-area sites. Eligibility is set by each program and by the site, so ask your recruiter before you plan around it.

Source: HRSA Health Professional Shortage Areas data warehouse, designated areas only. A designation can cover part of a county.

Registered Nurse pay in nearby cities

CityDistanceMedian payPopulation
Columbia, SC64 mi$38.51/hr144,788
Fayetteville, NC78 mi$39.07/hr209,496
Goose Creek, SC83 mi$38.76/hr50,352
Summerville, SC84 mi$38.76/hr52,625
Rock Hill, SC87 mi$40.76/hr75,798
North Charleston, SC89 mi$38.76/hr126,005

Registered Nurse jobs in South Carolina · Registered Nurse jobs nationwide

Registered Nurse salary in South Carolina

License and tax basics in South Carolina

South Carolina is in the Nurse Licensure Compact, so an RN or LPN/LVN with a multistate license from another compact state can work here without a new license. Nurses whose home state is not in the compact apply for a South Carolina license by endorsement.

South Carolina taxes wage income. Use your own rates in the take-home pay calculator.

South Carolina state guide · Nurse Licensure Compact guide

Florence city guide: hospitals, employers and licensing

Common questions

How much do registered nurses make in Florence, SC?

Registered Nurses in the Florence metro area have a median pay of $38.57 per hour, about $80,220 a year. The middle half earn between $31.14 and $53.39 per hour (BLS, May 2024).

Is Florence a good place for registered nurses once cost of living is counted?

Florence ranks 116th of 335 metro areas for registered nurse pay after adjusting for local prices, and 245th of 379 before adjusting. Overall prices run 13% below the U.S. average.

Who is hiring registered nurses in Florence?

We list 3 open roles with published pay from 2 employers in Florence. Your free report adds named employers and pay near Florence.

Do I need a South Carolina license to work in Florence as a registered nurse?

South Carolina is in the Nurse Licensure Compact, so an RN or LPN/LVN with a multistate license from another compact state can work here without a new license. Nurses whose home state is not in the compact apply for a South Carolina license by endorsement. Confirm with the board before you accept a role.

Is Florence in a shortage area?

HRSA lists 3 active primary care shortage designations that include Florence County. Shortage areas often have more openings, and some loan repayment programs cover clinicians who work at eligible sites.

What is the per diem for a travel assignment in Florence?

The federal per diem benchmark in Florence is $110 a night for lodging and $68 a day for meals and incidentals, about $1,246 a week (GSA, fiscal year 2026). Your actual stipend depends on the assignment and your tax home.

Does Valorem Health place registered nurses in Florence?

Yes. We place healthcare staff in Florence and across South Carolina. Tell us your profession and we email the roles open near Florence.

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What do employers near Florence pay registered nurses? Get the report.

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    Pay for your role at other hospitals

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    What they are offering now

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The Joint Commission Gold Seal of Approval: Health Care Staffing Services Certification, since 2022American Staffing Association memberNATHO member: National Association of Travel Healthcare OrganizationsNALTO member: National Association of Locum Tenens Organizations

Pay report · RN near Florence, SC
Valorem Health Shift ReportFrom your recruiting team · [email protected]

Your RN pay reportFlorence, SC · pay published by employers and employer-reported wage offers in federal filings

1Pay for your role at other employers

  • Select MedicalFlorence, SC · 4 postings$46.59/ hr$40–$53
  • NuForce, LLCFlorence, SC · 3 wage offers$40.00/ hr$38–$40
  • Carnegie Health And Life Sciences Inc.Lancaster, SC · 6 wage offers$40.00/ hr$38–$42
  • Carnegie Health And Life Sciences Inc.Chester, SC · 2 wage offers$40.00/ hr$40–$40

Median pay per hour, with the range each employer published or reported in federal filings.

2What they are offering now

Low$31Median$37.38High$51

20 RN postings with published pay in South Carolina, 17 of them posted in the last 30 days. Month-by-month history by employer comes with your full report.

3Open now: 20 RN roles

  1. RN Registered Nurse Home HealthPermanent
    $70k–$85k/ year
    Amedisys · Charleston, SC · posted today
  2. RN Registered Nurse Home HealthPer diem
    $35.00–$40.00/ hour
    Amedisys · Columbia, SC · posted yesterday

+ 18 more in your report. Each one has pay, shift and start date.

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