SC · Greenville · Updated October 15, 2026

Nurse Informaticist jobs in Greenville, SC

The median nurse informaticist pay in the Greenville area is $38.26 per hour ($79,580 a year), with the typical range running from $36.32 to $44.95. That ranks 260th of 379 U.S. metro areas for nurse informaticist pay, and 260th of 335 once local prices are factored in. The CMS hospital directory lists 4 hospitals in Greenville. Tell us your role and we email current openings near Greenville.

Nurse Informaticist pay in Greenville, SC

The metro median is in line with the South Carolina statewide median of $38.41 per hour. Nationally the median is $45.00 per hour. BLS counts about 9,460 registered nurses employed in the Greenville-Anderson-Greer metro area, 22.1 per 1,000 jobs. Employment is about as concentrated here than in the country as a whole (location quotient 1.04).

LevelPer hourPer yearCompared with U.S.
Lowest 10%$31.74$66,02029% below U.S. median
Lower quartile$36.32$75,55019% below U.S. median
Median$38.26$79,58015% below U.S. median
Upper quartile$44.95$93,500in line with U.S. median
Top 10%$47.26$98,3005% above U.S. median

How Greenville ranks

  • 260th of 379 U.S. metro areas by median hourly pay
  • 260th of 335 after adjusting for local prices
  • 6th of 8 South Carolina metro areas

BLS does not publish a separate figure for nurse informaticist. These numbers are for the broader category it belongs to, Registered Nurses.

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2024, Registered Nurses (SOC 29-1141), all industries. This is what employers report paying, not an offer for a specific role.

What your pay buys in Greenville

  • Overall prices in Greenville-Anderson-Greer run 7% below the U.S. average (index 93.3, U.S. = 100).
  • Housing is the biggest driver: 23% below the U.S. average (index 76.8).
  • Adjusted for local prices, a $38.26 median hour buys what $41.03 buys at the national price level, 9% below the national median.

Source: U.S. Bureau of Economic Analysis, Regional Price Parities by metropolitan area, 2024. Prices are for the metro area, not for a single neighborhood.

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Estimate your Greenville paycheck

Estimated weekly gross$1,377
  • Per year: $68,868
  • Per month: $5,739

Gross pay before taxes and benefits, from BLS pay levels for the Greenville-Anderson-Greer metro area. For take-home pay use the take-home pay calculator.

Hospitals in Greenville

CMS lists 4 hospitals in Greenville.

HospitalTypeOwnershipCMS ratingEmergency
Prisma Health Patewood Hospital
Greenville, SC
Acute careNonprofit5 of 5No
Prisma Health Greenville Memorial Hospital
Greenville, SC
Acute careNonprofit4 of 5No
St Francis-Downtown
Greenville, SC
Acute careNonprofit4 of 5Yes
Shriners Hospitals For Children
Greenville, SC
Children'sNonprofitNot ratedNo

Source: CMS Hospital General Information, public data. A directory of hospitals, not a list of our clients.

Nurse Informaticist pay in nearby cities

CityDistanceMedian payPopulation
Asheville, NC52 mi$38.81/hr94,992
Gastonia, NC72 mi$40.76/hr85,535
Rock Hill, SC76 mi$40.76/hr75,798
Athens, GA84 mi$38.43/hr128,691
Charlotte, NC90 mi$40.76/hr943,476
Huntersville, NC93 mi$40.76/hr67,087

Nurse Informaticist jobs in South Carolina · Nurse Informaticist jobs nationwide

What employers ask for, and tax basics in South Carolina

Nurse informaticists connect clinical practice and health IT, improving workflows and EHR tools.

  • Active RN license
  • Clinical experience plus informatics training or certification
  • EHR build or analyst experience

South Carolina taxes wage income. Use your own rates in the take-home pay calculator.

South Carolina state guide · Nurse Licensure Compact guide

Other healthcare roles in Greenville

Greenville city guide: hospitals, employers and licensing

Common questions

How much do nurse informaticists make in Greenville, SC?

Nurse Informaticists in the Greenville-Anderson-Greer metro area have a median pay of $38.26 per hour, about $79,580 a year. The middle half earn between $36.32 and $44.95 per hour (BLS, May 2024).

Is Greenville a good place for nurse informaticists once cost of living is counted?

Greenville-Anderson-Greer ranks 260th of 335 metro areas for nurse informaticist pay after adjusting for local prices, and 260th of 379 before adjusting. Overall prices run 7% below the U.S. average.

Where do nurse informaticists work in Greenville?

CMS lists 4 hospitals in Greenville, led by Prisma Health Patewood Hospital. Ask for the free report to see current openings and pay.

Do I need a South Carolina license to work in Greenville as a nurse informaticist?

South Carolina is in the Nurse Licensure Compact, so an RN or LPN/LVN with a multistate license from another compact state can work here without a new license. Nurses whose home state is not in the compact apply for a South Carolina license by endorsement. Confirm with the board before you accept a role.

Does Valorem Health place nurse informaticists in Greenville?

Yes. We place healthcare staff in Greenville and across South Carolina. Tell us your profession and we email the roles open near Greenville.

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Pay report · Informaticist near Greenville, SC
Valorem Health Shift ReportFrom your recruiting team · [email protected]

Your Informaticist pay reportTop-paying employers shown · your South Carolina list by name comes with the full report

1Pay for your role at other employers

  • Denver HealthDenver, CO · 1 posting$152.07/ hr$138–$167
  • Stanford Children's HealthMENLO PARK, CA · 1 posting$101.46/ hr$90–$113
  • CommonSpirit HealthLOS ANGELES, CA · 1 posting$67.81/ hr$55–$81
  • CommonSpirit HealthTACOMA, WA · 1 posting$62.82/ hr$47–$78

Median posted pay per hour, with the range each employer published. Request your South Carolina list

2What they are offering now

Low$37Median$53.34High$80

11 Informaticist postings with published pay in the US, 10 of them posted in the last 30 days. Month-by-month history by employer comes with your full report.

3Open Informaticist roles

Open Informaticist roles near Greenville, SC, each with pay, shift and start date, arrive with your report.

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