MO · St. Louis · Updated October 15, 2026

Registered Nurse jobs in St. Louis, MO

Registered Nurses in the St. Louis area earn a median of $39.69 per hour, about $82,560 a year, and the middle half of them earn between $33.06 and $46.53. That ranks 181st of 379 U.S. metro areas for registered nurse pay, and 220th of 335 once local prices are factored in. 11 open roles with published pay are listed for St. Louis. Tell us your role and we email current openings near St. Louis.

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Open Registered Nurse roles in St. Louis

More open Registered Nurse roles in St. Louis

50 more open roles from employers in St. Louis. Each employer’s range arrives with your free pay report.

PermanentPosted yesterday

Registered Nurse

American Renal Associates · St. Louis, MO

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  • Full-Time
  • Req P-103138
New this week
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All Registered Nurse jobs in Missouri

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Named employers near St. Louis, what they pay and the roles open now. Free for candidates, email only.

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Who is hiring registered nurses near St. Louis

EmployerRolesMedian pay / hour
Select Medical6$46.96
Veterans Health Administration3$55.13
AccentCare1$41.50
Amedisys1$36.06

Registered Nurse pay in St. Louis, MO

The metro median is 3% above the Missouri statewide median of $38.35 per hour. Nationally the median is $45.00 per hour. BLS counts about 33,660 registered nurses employed in the St. Louis metro area, 25.1 per 1,000 jobs. Employment is more concentrated here than in the country as a whole (location quotient 1.18).

LevelPer hourPer yearCompared with U.S.
Lowest 10%$29.80$61,98034% below U.S. median
Lower quartile$33.06$68,76027% below U.S. median
Median$39.69$82,56012% below U.S. median
Upper quartile$46.53$96,7803% above U.S. median
Top 10%$50.79$105,64013% above U.S. median

How St. Louis ranks

  • 181st of 379 U.S. metro areas by median hourly pay
  • 220th of 335 after adjusting for local prices
  • 2nd of 8 Missouri metro areas

Source: U.S. Bureau of Labor Statistics, Occupational Employment and Wage Statistics, May 2024, Registered Nurses (SOC 29-1141), all industries. This is what employers report paying, not an offer for a specific role.

What your pay buys in St. Louis

  • Overall prices in St. Louis run 5% below the U.S. average (index 95.1, U.S. = 100).
  • Housing is the biggest driver: 21% below the U.S. average (index 79.0).
  • Adjusted for local prices, a $39.69 median hour buys what $41.74 buys at the national price level, 7% below the national median.

Source: U.S. Bureau of Economic Analysis, Regional Price Parities by metropolitan area, 2024. Prices are for the metro area, not for a single neighborhood.

Estimate your St. Louis paycheck

Estimated weekly gross$1,429
  • Per year: $71,442
  • Per month: $5,954

Gross pay before taxes and benefits, from BLS pay levels for the St. Louis metro area. For take-home pay use the take-home pay calculator.

Travel assignment per diem in St. Louis

ItemFederal rate
Lodging per night$150
Meals and incidentals per day$86
Per week (7 nights, 7 days)$1,652
13-week assignment$21,476

Travel registered nurse assignments commonly pay housing and meals stipends. The GSA per diem is the federal benchmark for what those stipends can be tax-free. Whether a stipend is tax-free for you depends on keeping a valid tax home, so confirm with your recruiter and a tax professional. Compare with your offer in the travel pay calculator.

Source: U.S. General Services Administration per diem rates, fiscal year 2026 (average across months).

Hospitals in St. Louis

CMS lists 11 hospitals in St. Louis, 5 of the 8 rated ones with 4 or 5 stars. Hospitals are a major employer of registered nurses.

HospitalTypeOwnershipCMS ratingEmergency
Missouri Baptist Medical Center
Saint Louis, MO		Acute careNonprofit5 of 5Yes
St Louis-John Cochran Va Medical Center
St. Louis, MO		Acute Care - Veterans AdministrationGovernment and federal5 of 5Yes
Barnes Jewish Hospital
Saint Louis, MO		Acute careNonprofit4 of 5Yes
Christian Hospital Northeast
Saint Louis, MO		Acute careNonprofit4 of 5Yes
Mercy Hospital St Louis
Saint Louis, MO		Acute careNonprofit4 of 5Yes
Ssm Health St Mary's Hospital - St Louis
Saint Louis, MO		Acute careNonprofit3 of 5Yes
Mercy Hospital South
Saint Louis, MO		Acute careNonprofit2 of 5Yes
Ssm Health Saint Louis University Hospital
Saint Louis, MO		Acute careNonprofit1 of 5Yes
Shriners Hospitals For Children
Saint Louis, MO		Children'sNonprofitNot ratedNo
St Louis Childrens Hospital
Saint Louis, MO		Children'sNonprofitNot ratedYes

Source: CMS Hospital General Information, public data. A directory of hospitals, not a list of our clients.

Primary care shortage areas in St. Louis city

HRSA lists 5 active primary care shortage designations that include St. Louis city (2 population-group, 3 facility). The highest-scoring one rates 24 on a 0 to 25 scale, where a higher score means a greater shortage.

Shortage areas are where demand for nurses, nurse practitioners, physician assistants and other clinicians is greatest. Federal loan repayment programs such as the NHSC and Nurse Corps cover some clinicians who work at eligible shortage-area sites. Eligibility is set by each program and by the site, so ask your recruiter before you plan around it.

Source: HRSA Health Professional Shortage Areas data warehouse, designated areas only. A designation can cover part of a county.

Registered Nurse pay in nearby cities

CityDistanceMedian payPopulation
Florissant, MO12 mi$39.69/hr51,290
St. Charles, MO18 mi$39.69/hr72,458
Springfield, IL86 mi$39.27/hr112,949
Decatur, IL110 mi$40.44/hr68,763
Columbia, MO114 mi$39.12/hr130,900
Bloomington, IL144 mi$38.49/hr79,232

Registered Nurse jobs in Missouri · Registered Nurse jobs nationwide

License and tax basics in Missouri

Missouri is in the Nurse Licensure Compact, so an RN or LPN/LVN with a multistate license from another compact state can work here without a new license. Nurses whose home state is not in the compact apply for a Missouri license by endorsement.

Missouri taxes wage income. Use your own rates in the take-home pay calculator.

Missouri state guide · Nurse Licensure Compact guide

Other healthcare roles in St. Louis

St. Louis city guide: hospitals, employers and licensing

Common questions

How much do registered nurses make in St. Louis, MO?

Registered Nurses in the St. Louis metro area have a median pay of $39.69 per hour, about $82,560 a year. The middle half earn between $33.06 and $46.53 per hour (BLS, May 2024).

Is St. Louis a good place for registered nurses once cost of living is counted?

St. Louis ranks 220th of 335 metro areas for registered nurse pay after adjusting for local prices, and 181st of 379 before adjusting. Overall prices run 5% below the U.S. average.

Who is hiring registered nurses in St. Louis?

We list 11 open roles with published pay from 4 employers in St. Louis. Your free report adds named employers and pay near St. Louis.

Do I need a Missouri license to work in St. Louis as a registered nurse?

Missouri is in the Nurse Licensure Compact, so an RN or LPN/LVN with a multistate license from another compact state can work here without a new license. Nurses whose home state is not in the compact apply for a Missouri license by endorsement. Confirm with the board before you accept a role.

Is St. Louis in a shortage area?

HRSA lists 5 active primary care shortage designations that include St. Louis city. Shortage areas often have more openings, and some loan repayment programs cover clinicians who work at eligible sites.

What is the per diem for a travel assignment in St. Louis?

The federal per diem benchmark in St. Louis is $150 a night for lodging and $86 a day for meals and incidentals, about $1,652 a week (GSA, fiscal year 2026). Your actual stipend depends on the assignment and your tax home.

Does Valorem Health place registered nurses in St. Louis?

Yes. We place healthcare staff in St. Louis and across Missouri. Tell us your profession and we email the roles open near St. Louis.

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What do employers near St. Louis pay registered nurses? Get the report.

Tell us your role and city. Within 24 hours you get an email with three things, by employer name. It costs you nothing, because employers pay us.

  1. 1
    Pay for your role at other hospitals

    The hourly pay at named employers near you, so you see who pays most.

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    What they are offering now

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Pay report · RN near St. Louis, MO
Valorem Health Shift ReportFrom your recruiting team · [email protected]

Your RN pay reportSt. Louis, MO · pay published by employers and employer-reported wage offers in federal filings

1Pay for your role at other employers

  • Veterans Health AdministrationKansas City, MO · 8 postings$52.14/ hr$33–$76
  • Select MedicalSaint Louis, MO · 9 postings$46.00/ hr$34–$56
  • University of Missouri Health CareColumbia, MO · 2 postings$39.56/ hr$30–$51
  • Truman Medical Centers, Inc.Kansas City, MO · 2 wage offers$32.45/ hr$32–$33

Median pay per hour, with the range each employer published or reported in federal filings.

2What they are offering now

Low$34Median$46.61High$62

22 RN postings with published pay in Missouri, 21 of them posted in the last 30 days. Month-by-month history by employer comes with your full report.

3Open now: 22 RN roles

  1. Registered Nurse - Outpatient Mental HealthPer diem
    $75k–$154k/ year
    Veterans Health Administration · Saint Louis, MO · posted today
  2. Registered Nurse - Mental HealthPermanent
    $75k–$154k/ year
    Veterans Health Administration · Saint Louis, MO · posted today

+ 20 more in your report. Each one has pay, shift and start date.

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